- PK program studies
- Routine single or multiple dose PK studies
- Oral, ocular, dermal, intratracheal, intravitreal, intravenous, intramuscular, subcutaneous, intrapretoneal, joint fluid, short-infusion and other routs of administration.
- Pharmacokinetic-pharmacodynamic studies in disease models such as tumor-bearing animals, infection models, inflammation models, metabolic diseases, and surgical animals
- Radionuclide studies
- MRSA nasal inoculations
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- Pharmaceuticals
- Proteins
- Other biotech products
- Veterinary products
- Synthetic organic chemicals
- Pesticides
- Food additives
- Stem cell
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Isolated organs of animals are perfused
by an artificial blood circulation system
with body-warm whole blood. The most
modern methods from the internal medicine
and from the transplantation medicine are
used. Substances and cosmetics can be
tested in such a way. The effect of a
substance on a defined organ can be
examined without interference by other
organs.
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Studies have utilized numerous species of laboratory animal models in SPF conditions, including:
- Rodents
- Minipigs
- German domestic pigs
- Goat
- Sheep
- Dogs
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- Implantation testing
- Function testing
- Local irritation testing
- Biocompatibility testing
- Pyrogenicity testing
- Sensitation testing
- Physician hands-on-training
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| Classes of medical Devices |
- Coronary stent
- PFO, ASD catheter
- Cardiovascular catheter
- Central venous catheter
- Pacemaker
- Artificial heart
- Artificial valve
- Indwelling catheter
- Peritoneal catheter
- Intracarneal pressure measurement
- Orthopedic device
- Bone cement
- Bone substitute
- Cartilage substitute
- Bone marrow aspiration
- Scaffold
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- Gavage, dietary, ocular and dermal
- Intravenous, intrapretoneal, subcutaneous injection or infusion
- Intratracheal and intranasal instillation
- Nasal inoculation
- Intravitreal
- Intraventricular and intraaortic
- Intrahecal, intravaginal
- Single dose and multiple dose
- Continuous dosing using osmotic pumps
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